Taking Tecfidera

So, I was very excited/nervous to start Tecfidera. After taking 3 other medications and them not working out… I hadn’t been on any medication for a few months. So, for the first week, I took have the “normal” dose, twice a day. The side effects I experienced were what I expected.

If you’re looking at the information posted about it, it states that the common side effects are GI problems, but studies showed that it would go away after a month.

Sure enough, I’ve been taking it for a little over a month, and I am not experiencing any of the side effects anymore. But unfortunately, I’m dealing with my MS symptoms that hate this Texas Heat!

I’m not saying that the medication was simple with no side effects at all. But compared to what I’ve dealt with in the past with the other medications I have taken (which are Avonex, TYSABRI & Copaxone, in that order). So I have dealt with the Flu and Site Reactions, etc. For me, the side effects for Tecfidera were mild. It’s nice to be able to just add the pill into my daily medication schedule, rather than prepping for shots and stuff.

Were there times where I did dislike the medication from the side effects? Yah, no doubt. But I kept thinking about the long-term goals; how I want this medication to work for me and help slow the progression of my MS.

I think that every medication has it’s own set backs, it’s just up to you to debate the pros and cons.

I know that a lot of people are wondering about Tecfidera – and that’s why I wanted to kind of give an insight into how I was doing on it. Of course, it doesn’t help my MS symptoms… and we don’t really know how it’s working until we do an MRI (after taking it for a while), but as far as how it makes me feel… I don’t feel any different than normal, now that I’ve gotten passed that first month of side effects.

They even sent me a little pill box, it holds your daily dosage for a week:

TecfideraPillBox2 TecfideraPillBox

I have come to the realization that there isn’t going to be this magic pill that is a “DMD” that you won’t experience any side effects with. I hope we get it, but that just isn’t reality at the moment.

If you just want to know more about Tecfidera, you can also go to their website:
Tecfidera.com.

I’ll let y’all know how things go!

xoxo

Ashley Ringstaff

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This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The MultipleSclerosis.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

Comments

View Comments (48)
  • Smilsen
    4 years ago

    Hey y’all, I’m new to this site and really in search for help/support. I am 20 years old and was diagnosed with MS 8 years ago. I have been on copaxon, gelynia and now tecfidera. I started tecfidera about 2 weeks ago I completed my 1st week on the 120 mg and went on to the higher doze last week and 2 days ago I broke out into a rash, my skin was red and I wanted to scratch my skin off! ( almost went to the ER) I sat in cold water, took 2 benadryls and cried and went into an anxiety attack bc it wasn’t getting any better. Eventually I fell asleep and woke up better the next day I called my neurologist and they told me to get off it for a day and I did. Today I received a call to take aspirin 30 min before I take the tecfidera again and see if that helps and now I’m itching again 🙁 I hate MS. That’s all thanks for listening to my rant.

  • calculus
    5 years ago

    I am new to this site. Just happened to stumble on it and decided to join. Just started tecfidera. Today is day 4 and no side effects at this point. I am however following the strict guidelines from my nurse case manager. Her recommendation is to take 325 mg. aspirin(not enteric coated) 30 min before taking tecfidera. I eat during the 30 minutes always including some fat,carbohydrates and protein. Before taking the tecfidera I take 3 tums as well. Not sure if all this is necessary but I am having no problems. The one thing I find difficult is keeping to the 10-12 hour interval. Makes it hard to sleep late on the weekends. Would love some input about this. I guess if you don’t take it with food it could be easier to follow this time frame. Look forward to any response.

  • christie
    5 years ago

    I have been on Tecfidera for about 2 1/2 weeks now and i have only had flushing may be 4 times and no stomach issues. I have found that taking the meds with a glass of chocolate milk helps tremendously. This is my first med as I was recently diagnosed but I dont feel any different i am still having vision issues, pain in my extremities, and fatigue

  • Lasangela
    5 years ago

    How long do the stomach issues last? I’ve started my second month of Tecfidera and the stomach issues are more intense. I use carafate, gas X, tums, peppermint, food, toast, and a heating pad. Still hurts! Wondering how long before it decreases. Happy to hear other suggestions for management as well.

  • Pvilla
    5 years ago

    I was dx with MS a few months ago….other than a bout of optic nueritis I have had NO OTHER SYMPTOMS!!! I am desperate for some advise…my nuerologist would like me to start Tecfidera…I am scared. I am not sure if I should just wait until I have symptoms (the Optic Nueritis is gone now) or be proactive and start meds now…thanks all!

  • technical
    5 years ago

    Stomach problems getting better, stick with it!

  • SM21
    5 years ago

    I was on Rebif for almost 10 years. I didn’t have any MS episodes or any problems with the Rebif. I was just tired of the needles and I was anxious to switch to Tecfidera. I have been on Tecfidera for 14 days and I am so glad I switched.  I have had minimal side effects, occasional flushing and small GI upset, but neither is painful. I read previous reviews that suggested taking the pills with heavier foods and I take them exactly 12 hours apart. Honestly, I was a little nervous about making the switch, but I am so happy I did. I hope this review helps others with MS that are considering Tecfidera. It has made my quality of life better so far!

  • technical
    5 years ago

    Her is the deal, eat, take pill why u are eating, also take a Pepcid or something like it. One shot of Malox or something like it. I was also told to take a square of dark chocolate, trust me it helps the flushing. The aspirin is no good cause it hurts your belly. Then if you are still awake and the stomach cramps start, even if you have no appetite and don’t want to, eat some dry toast or crackers and some water. Then you have about 20m left of the worst cramping. I found that rocking back and fourth seems to help it. That is my every nite routine. Also when you start the next day, eat some Greek yogurt, it really helps your gut. One week to go and then i start the 240mg twice a day, not looking forward to it, but hey, sure beats the needle! Good luck to all, don’t give up!

  • Pvilla
    5 years ago

    How are you feeling now?

  • westwind
    5 years ago

    I have been on Tecfidera since May and it took about 2 for the nausea to stop. NOW THAT IT HAS THInGS ARE GOING FINE. I have not yet noticed any other changes. it is to soon I think.

  • Pvilla
    5 years ago

    That’s great! I am starting this week, very scared, hoping no side effects!

  • Sandy
    5 years ago

    Ashley,
    I DID get to start Tecfidera after all. BIOGEN set me up until this time next year. (GOD is GOOD)
    I’m starting my second month, and so far, have had no real side effects to speak of. I’m dealing with ALABAMA heat (and humidity) as well, so that ain’t no fun !
    But, so far, so good. I’ll keep you posted. All the best !
    Sandy

  • Musicang
    5 years ago

    I have always had GERD (basically bad acid reflux). I have been taking Tecfidera since June. I get some stomach issues if I don’t take it with a meal, and I am even more careful about staying away from acidic and spicy foods. I also take Prevacid which I was on before starting Tecfidera. I have found ice cream or milkshakes to be great friends when my tummy is upset by this med. (Oh darn, right?)

  • Sue
    5 years ago

    Day 3 on Tecfidera and so far, so good! Only minimal flushing on Day 1 and a little upset stomach on Day 2. Nervous about the dose doubling next Sunday, but I am pretty tolerant so hopefully this will continue. Prayers for and hugs to all of you!

  • Berserker1
    5 years ago

    I was without a DMD for over a year after losing insurance for my copaxone.
    I now have been taking tecfidera for just on two months with no side effects. It is nice to put the worry of no DMD behind me again and knowing that at least I am doing something that may keep this MS critter at bay.
    I am relapsing remitting headed I feel after 15 years to the next stage….time will tell.
    Neil

  • lynne
    5 years ago

    I just had all of my blood work done to check if the Tecfidera was effecting the liver and my CBC for white and red cells and everything came back perfect so far so good. Everything I have read on Tecfidera appears promising. Hang in there everyone and good luck.

  • lynne
    5 years ago

    I started Tecfidera back in May of this year. The first month was rough as I had flushing pretty bad and nausea, however within 30 days the side effects subsided and now I only have flushing on occasion and it is mild. I hope as more time goes by it will stop all together. Other then that, it is such a relief to just take a pill twice a day. If you have memory issues, find some way to set an alarm on your cell phone to remind you to take it the same time each morning and evening, 12 hours apart. This is the hurdle I am trying to get over. When my alarm goes off if I don’t take it right then and there I forget but my short term memory is really bad so I continue to work on this. I was on Betaseron injections for 7 years and I loved them. No side effects at all, however after 7 years my neutralizing antibodies went through the roof and I had to switch to Copaxone. Copaxone worked as far as no progression on MRI but the side effects were horrible. Site reactions were rough and I finally got shot burn out and so my doctor switched me to Tecfidera. Now being on it for 3 months it is so nice just to take the pill. I am hopeful for this drug but I won’t know until next year when I have another MRI if it works as well as the injections. Keeping my fingers crossed. If you are waiting to start Tecfidera don’t worry I believe you will find it so much easier then any of the injectables. And ladies I am in Texas and I get the heat as well. I feel like a prisoner in my own home through the summer months, its just way to hot for us MSer’s. Good luck to all.

  • Christine
    5 years ago

    Thanks for all the input. I am waiting for an approval for Tecfidera from my Insurance Company. I have tried Copaxone (hate needles)It left unsightly divets on my thighs, and Tysabri weakened my immune system. So I hope these meds work better for me. I don’t have a problem with the twice a day pills. What I have a problem with is this life changing illness.~~:( Thanks to everyone for posting.

  • Len
    5 years ago

    I was dianosed in August 2012 and Copaxone seemed to be the best choice for me as it had the least amount of side effects. However, I also have to take blood thinners due to some other problems and the shots would frequently make me bleed for quite a while. Then I heard about Tecfidera and talked to my neurologist about it as it sounded perfect for me. Then, of course, my insurance company denied it and I had to go through several rounds of appeals until it was finally approved for me to have. I started on it four weeks ago.

    I cannot tell you how much better I feel. I take it with food in the mornings and evenings and have not had any “issues” whatsoever so, for me, it has been tremendous. Even people I work with have made comments about how I look like I feel better, my eyes are brighter and I just look and feel healthier. I know not every medicine is perfect for every person, but for me it has been great.

  • Cathie
    5 years ago

    After 11 years of Copaxone, which I did very well on I wanted to try Tecfidera because I was so tired of injections. So I received the medicine and took the week long dose of 120 mg twice a day. All was good then I began the maintenence of the 240 mg twice a day. I was so sick, first we thought I had food poisoning then we realized everything I ate made me very sick. Cramps that made we want to die. I should mention I am under 5 feet and barely 100 pounds. The thought of over dosing comes to mind as the 240 mg is to much. My doctor has taken me off the medicine until it can be determined if I can continue onthe lower dosage.

  • Donna Rivera
    5 years ago

    I have that same pill dispenser 🙂
    Anyway, I’m halfway through my second month of Tecfidera. The side effects are mostly flushing and it comes and goes, I think, depending on how tired I am. That’s the worse. I was taking copaxone since my diagnosis in 2010 (diagnosed at age 52). Copaxone did nothing for me. I felt like I was shooting water. Conversely I also had additional lesions, which is why I’ve switched to Tecfidera. I’m keeping my fingers crossed. I’m feeling good.

  • Anastasia
    5 years ago

    I’ve been on Tecfidera 3 weeks. First week at 120mg was no problem.
    Second week with 240 mg twice a day-was Bad! Every other day, I have either diarrhea or nauseA.
    Just started 3 week, dr says take 240mg once at dinner. Oh no, diarrhea every other day
    Do I continue?????

  • Lisa
    5 years ago

    I am so glad to see this discussion. I was on Copaxone with NO side effects but just stopped doing the whole needle thing because it gave me anxiety. I failed Gilenya miserably and decided to not do anything for about a year. Well I had a flare up that required the old 3 days of steroids. So the doctor recommended Advonex. I really, really tried to make this work. The self injector did not bother me. I stayed on it for 90 days and 30 days out of that was deathly ill with more than what I would call flu like symptoms. The Neurologist called me last night and after a lengthy conversation (I have an awesome neurologist), my husband and I are deciding to try Tecfidera. Waiting 2 weeks to flush Advonex out and then will attempt this one. I’ll let everyone know how it goes but hoping it won’t be bad. Between Advonex and Gilenya I am not sure which one was worse for me. I’ll let everyone know how it goes.

  • stukawife
    5 years ago

    I am nearly through my first week. I have no side affects at all. i could have been taking this 6 weeks sooner if Curascript hadn’t totally screwed up my order and then liet to me when i called them on it.

    I’ve taken Avonex, Rebif, Betaseron and LDN. So I am hoping this does something.

  • lorih
    5 years ago

    I am now on day 26 of Tecfidera. Was on Avonex since my diagnosis in 1999. Could no longer take the flu-like symptoms and migraine headaches that took 2 days out of every week. I have not had an attack for about 6 years and I am doing well except for some fatigue and episodes of numbness that start at my feet and goes up to rib area. They are very painful in a strange sort of way that’s hard to describe. About the third day on the starter pack is when the gastro problems started. I was taking uncoated aspirin as per instruction but stopped that on the third day as I have GERD and felt the aspirin was aggravating it. As I hadn’t had any flushing I felt it wasn’t necessary. By day 5 I had severe stomach and abdominal cramps and was going to the bathroom a lot but I never developed diarrhea. Then it switched on me and it seemed like I was constipated as I wasn’t going at all. After dealing with pain, cramps, nausea and gas for a couple of weeks a pharmacist suggested I take something for GERD before I ate which helped tremendously. For awhile I had no appetite and was only eating so I could take my Tecfidera. Since I am menopausal I had difficulty pinpointing what was because of the Tecfidera. Finally I realized that my ‘flushing’ was when I was sweating at the hairline and hot all over. On day 25 (yesterday) after feeling quite good for a couple of days meaning no gastro problems I realized I had a yeast infection. I bought an over the counter generic brand of Fluconazole 150 mg which is the standard medication – it was one dose of one capsule. I took this at 5PM with no problems and then took my Tecfidera dose at 7 PM after supper. Within 20 minutes I was sweating from my hairline, was extremely hot and extremely itchy. Then my lips and the left side of my face started to swell. I had extremely itchy areas with redness and swelling on the inside of my wrists and itchy red areas on the joints of my thumbs and on my elbows. I had huge hives scattered all over. I took Benadryl 50 mg which relieved the terrible itchiness but the swelling continued to the point where the inside of my left lip was swollen also and my lip looked blue. I had no breathing or swelling of the throat or tongue. I took another 50 mg dose of Benadryl at bedtime and this morning when I woke up the swelling was down considerably but the swelling had progressed to the
    rest of my lips. The rashly areas were still quite prevalent. I took another dose of Benadryl yet my lips continued to swell. After notifying Biogen and my MS doctor I saw my family doctor who said to keep on the Benadryl every four hours so I took another dose at 2:30 PM. I started to feel kind of out of it, shaky and dizzy so I decided not to take another dose until bedtime. My lips are better but nowhere near normal yet and an occasional itchy huge hive appears. The left side of my face is still slightly swollen. Since the symptoms appeared right after my dose the thinking is there is some contraindications between the two drugs. I have taken Fluconazole in the past and never had a problem. So I was told by my doctor and the Biogen nurse not to take anymore until I hear from my MS doctor. I thought since the medication for the yeast infection is the usual remedy that I should tell my story for all the women out there that could find themselves in the same situation and advise caution.

  • Jessica P.
    4 years ago

    Amy, I too have noticed anxiety attacks. I get them for maybe an hour or so, but they have been pretty intense. I also have noticed the flushing and itching. I thought I was the only one because I have been reading up on Tecfidera and have not seen anyone have the same complaint!

  • amy
    5 years ago

    I was diagnosed in 1995 and i’ve was on copaxone for 11 years. I decided to change my therapy…..i am now on week 7 with tecfidera. I have read the comments and feel better knowing that I am not alone with the flushing, but I haven’t heard anyone else having anxiety attacks! They begin about 20 minutes after taking my dose and last about 15 minutes then the itching and burning start, that lasts about 20 minutes. I don’t want to stop the meds cuz i feel better (after all the side effects)I hope it at least will become more manageable. Has anyone else dealt with anxiety attacks?

  • EmilyJ
    5 years ago

    I have been on Tecfidera for two months. I took Copaxone for 11 years and just got needle fatigue. Surprisingly, the only side effect has been a slight flush feeling and sweat at my hairline which lasts for a few seconds. This does not happen often so it’s not a big problem. I was told this would subside in about 3 months. All in all, I am happy with the choice.

  • Susan
    5 years ago

    I’ve been reading here for awhile but just signed up to participate. I was dx in 1996 so I have been living with ms for awhile. I use a walker around my apartment but a manual wheelchair for distance.

    I just saw my neuro yesterday and signed the paperwork to start tecfidera. I was on aubagio for a month when I had an allergic reaction to it. Before that I did tysabri for 18 months but quit that when it was depressing my immune system too much and I ended up in the hospital twice in three months. Once with a uti that I didn’t even know I had that went bonkers immediately after an infusion and turned into sepsis. The second time I came down with bacterial and viral pneumonia and the flu at the same time within a few days of an infusion. That was enough of that!

    I didn’t due well on avonex – it gave me wonky liver enzyme test results after about six months. I did copaxone for five years until I lost my job and insurance. I was on nothing for about seven years as I had no insurance. Then tysabri came along with their generous program.

    I just had insurance kick in 8/1 so I have no idea how they will react to tecfidera. Guess ill find out in time. I appreciate everyone sharing their experiences with side effects so I have an idea what to expect.

    Thanks for letting me chime in!
    Susan

  • Musicang
    5 years ago

    Tecfidera has an income based program that may cover your meds entirely! I was shocked when I qualified. Call the number for financial aid on the Tecfidera.com website!

  • stukawife
    5 years ago

    Tecfidera paid $40 of my $50 co-pay.

  • lori
    5 years ago

    I too just started Tecfidera this past sunday. dr started me on only 1 tab a day for the 1st week as I have had a major(reaction) taking every injection out there except for Avonex. but w/it had the severe flu like symptoms. unable to be on the other 2 pills, tysabri was doing ok till the rise in deaths after 24 mths, so my dr and I decided to stop. am praying I will be able 2 continue only taking a pill. I hated those shot nights. I would cry and even started not taking once in awhile, didn’t want to go thru 2 days of being sick.
    2 out of 6 doses had the redness and itching. but they were minor compared to past reactions. will see how it goes as I go up on the doses.
    also wondering where anyone got the neat pill holder.
    hopefully this new med w/ lesser side effects will be something more people can take.
    To those of you having problems with the heat. I live in Pa. Most of the yr will find in short and sleeveless tops and seeking a.c. Not all mine is from the m.s. some is from menopause and thyroid. winter will still find me w/ heat close to only 60/62 degrees.
    prayers to all of u out there dealing with m.s.

  • Budcrab
    5 years ago

    I’m glad to read the comments on Tecfidera from you who have and are trying it. I was diagnosed with MS in 2009 at 52 and have been on Beta Seron since. While I haven’t been having any problems the last couple of years with lesion development, some of my symptoms have intensified somewhat so my neurologist wanted to try either Copaxone, Tysabari, or Tecfidera. After the blood tests, Tysabari was a no-go and I told him I thought I liked what I was reading and so we are now in just waiting for the final approvals from my insurance and from Biogen to get it started! I am anxiously waiting!

  • blondie
    5 years ago

    Why was the Tysabari a no go? Tecfidera also poses risk for PML if that is reason. I took the 120 bid doses ok with flushing that I could deal with. When I went up to the 240 dose I had a severe reaction and the flushing hurt so bad I couldn’t hardly breath. I literally was purple with blue lips and fingernails. I can not tolerate the injections so I am at loss as to what I can do. Prednisone is out of the equation also as I have severe reactions to this also. Tachycardia to the point of being unable to breath. I can do betamethasone in 3 ml doses. I have been dealing with a relapse for about 8 weeks now. Optic neuritis has been a nightmare as my alt. income is photography. I also work in the medical field so compromised immune systems are not a good idea. So waiting till I can see my neuro. (in Oct.) to see what the options are now.

  • Kathy Lacour
    5 years ago

    I don’t have any side effects with Tecfidera.

  • TexMSgirl71
    5 years ago

    I’ve been on Tecfidera for about 3 weeks now and like Ashley said the GI problems are not bad. Did not care for the flushing because it made me freak out a little. Avonex has been with me for 12-13 years now and while I was used to the needles, I hated them with a passion. My relapsing/remitting dx has been a blessing so I will not complain about anything as I read there are others who have it so much worse. I am wondering is anyone else worried about the whole “causes cancer in lab rats” thing?
    Oh and I am hoping to avoid another optic neuritis in the future… Scared me half to death! Hope everyone else is handling this heat! Living here we are used to it but it consumes my life to try keeping cool. Hope all of you MS’ers are doing good considering!! Love from Texas 🙂

  • Lori
    5 years ago

    I am starting my 2nd month of Tecfidera. I must say this has been the best that I have felt in many years. I have been on Rebiff, Avonex, Copaxone, Betaseron & ended with Tysabri. As soon as Tecfidera came out & was out for a couple months I said I have to try. I have failed so many others. I do get some itching but that is about it. People now know who they are talking to on the telephone. I feel stronger. I will enjoy & hope this will last. It will I can feel it. This has been the best move I have made in a very long time. I wish all the best & keep smiling & keep praying.

  • Pam J
    5 years ago

    Re itching — forgot about that. Wonder why I was itching. Mostly in middle of night,kind of all over. I take a Hydrox HCL

    Have a recent bite ?? On bottom of foot – wonder if that caused itching.
    I’ve been on it all. Even in the infamous Beterseron lottery ( I won but built up antibodies. Liked Tysabri the best – 54 months w/ JC+ but then got strong sense to go off it.
    Some nausea w/ Tecfidera only my second week. Hugs

  • TexMSgirl71
    5 years ago

    Lori I’m with you I forgot about the itching! I woke up clawing my neck which was weird but like I said, it has not been bad.
    I’ll send up a prayer. I understand about feeling stronger after an attack and then trying to overcome the steroids. It feels like being hit by a truck to me.
    Much love…

  • Mrs. Jones
    5 years ago

    I am to start Ticfidera soon. I am nervous also. working on getting patient. My Copay is crazy high & Insurance like always say’s no. I had a horrible shot reaction. That is why I am able to switch. Thanks for sharing! Richelle

  • sobanion
    5 years ago

    Thank you!! I will start Tecfidera soon and so nice to read about someone else’s experience. I was diagnosed in 2006…been on Copaxone and Avonex. Thank you so much for sharing.

  • missyd
    5 years ago

    My Dr too wants me to start on Tecfedera. I am currently on Copaxone and have been diagnosed since Nov 2011. I am nervous on the what the side effects might be because I never had the stomach problems on Copaxone. I really appreciate hearing from you guys who are trying this new drug. Please keep updating on it. Knowledge is Power. Thanks

  • Sue
    5 years ago

    Anyone out there taking Tecfidera who is also a type 1 diabetic? I have heard that Tecfidera causes blood sugars to go low; am interested in finding out more about this before I start on Tecfidera on September 1.

  • TexMSgirl71
    5 years ago

    Sue I have only heard that about Solu-Medrol and it is true true true! It is tough to get over but very necessary if you have an attack. The only drug I have ever taken that has worked to stop an attack!

  • Sonya
    5 years ago

    Hi Ashley!
    Thanks for your comments on Tecfidera! I saw my neurologist a few weeks back, took home the packet of info, researched & researched some more, decided I could do this, then I got ill. They thought at first it was a stomach bug, now they don’t know for sure. Had a CT scan done on Monday, haven’t heard back from it.
    I’m so happy to hear you are doing o.k. on this med. I sincerely hope & pray you continue to do good. Look forward to hearing how things progress for you.
    Best of luck!
    Sonya

  • GDJSS
    5 years ago

    Please keep us posted. After misery with copaxone and avenox myself I have my Tecfidera and its little pill case. Planning to start Aug 8. Good luck to all of us!

  • Sandy
    5 years ago

    Waited months for FDA to approve Ticfidera, was all set to start, and my insurance insisted on me trying another ABC drug first. Previously on Rebif, which caused some pretty bad site reactions (and I despise giving myself a shot)
    So, gearing up for a run of avonex, but just as soon as I can, I WILL be going on Ticfidera, and I appreciate your input on how it’s going, so far. Please keep us updated.
    Thanks,
    Sandy/Alabama (so, I GET the heat too) !!!

  • Sonya
    5 years ago

    Hi Sandy!
    Bummer on the insurance deal!
    I too was ready to start Tecfidera, but became ill with stomach problems. Hopefully they can figure this out, & I can start soon.
    I just wanted to say, I have been on Avonex for over 6 years. I also hate those dang shots……I know I should be grateful for anything which may keep this disease at bay, & I am….I just HATE the shots! I would be glad to share my experience with the injections, if you want to know. Some people prefer not knowing. Just let me know~
    I too am in the south…..Georgia….so the heat is a big factor for me too. I received one of the sport towels, that you wet & place around your neck, for my birthday. It seems to help me some. I feel I can stay out longer with it, than without.
    I pray you have good luck with the Avonex, & zero to minimal side effects:-)
    Sonya

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