"I recently had my last infusion of Tysabri in March. I need to switch medications and am researching what my best option is at this point. I have previously been on Copaxon-caused severe reaction to injection sites and hives, aubagio-had new lesions, rebif-severe reaction to injection sites, and tysabry-severe hives and increased JCV level. I don't want to be off medications for too long. Any suggestions/thoughts are greatly appreciated"