MS Research Spotlight: Comorbidities, Disability Milestones & More
This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The MultipleSclerosis.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.
- Marrie RA. Comorbidity in multiple sclerosis: Past, present and future. Clinical and Investigative Medicine. 2019 Mar 23;42(1):E5-E12. doi: 10.25011/cim.v42i1.32383.
- Beiki O, Frumento P, Bottai M, Manouchehrinia A, Hillert J. Changes in the Risk of Reaching Multiple Sclerosis Disability Milestones In Recent Decades: A Nationwide Population-Based Cohort Study in Sweden. JAMA Neurol. Published online March 18, 2019. doi:10.1001/jamaneurol.2019.0330
- Kurtzke Expanded Disability Status Scale. US Department of Veterans Affairs. https://www.va.gov/MS/Professionals/Diagnosis/Kurtzke_Expanded_Disability_Status_Scale.asp. Updated August 3, 2018. Accessed April 18, 2019.
- Block VJ, Bove R, Zhao C, et al. Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis. JAMA Netw Open. 2019;2(3):e190570. doi:10.1001/jamanetworkopen.2019.0570
- Hostenbach S, Pauwels A, et al. Role of cerebral hypoperfusion in multiple sclerosis (ROCHIMS): study protocol for a proof-of-concept randomized controlled trial with bosentan. March 14, 2019. ttps://doi.org/10.1186/s13063-019-3252-4
- Duncombe J, Kitamura A, Hase Y, et al. Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia. Clinical Science. September 28, 2017. DOI: 10.1042/CS20160727
- D'haeseleer M, Hostenbach S, Peeters I, et al. Cerebral hypoperfusion: a new pathophysiologic concept in multiple sclerosis?. J Cereb Blood Flow Metab. 2015;35(9):1406–1410. doi:10.1038/jcbfm.2015.131
- UZ Brussel. Does cerebral hypoperfusion play a role in reduced axonal metabolism and clinical disability in patients with multiple sclerosis? EudraCT Number: 2017-001253-13. Start dateL August 23, 2017. Accessed April 18, 2019.