Long before I was diagnosed with MS I had problems with fatigue, which have only gotten worse, and I know this is a problem that is widely shared. I’m wondering about the differences between Amantidine and Modafanil. Have any of you had experiences with both drugs? How would you rate their effectiveness? I’m sure some of the differences have to do with the individual patient, just like MS is different for each of us. Still, I’d appreciate hearing about your experiences.