Managing the Disease Course
Reviewed by: HU Medical Review Board | Last reviewed: June 2025 | Last updated: June 2025
Although multiple sclerosis (MS) does not have a cure, there are many drugs you can take to help treat the disease. These drugs, called disease-modifying therapies (DMTs), help prevent permanent damage to your central nervous system (CNS). This damage can occur early in the disease, even when you feel well and do not have symptoms. That is why treatment with DMTs should begin as soon as possible after diagnosis.1
What are DMTs?
DMTs have been shown to reduce the number and severity of attacks or relapses that people with MS have. By preventing new lesions, DMTs can slow the damage to the brain and spinal cord caused by MS. They can thus slow down the progression of disability.1
Several DMTs are approved by the U.S. Food and Drug Administration (FDA) for treating MS.1
Injected treatments
- Avonex® (interferon beta-1a)
- Betaseron® (interferon beta-1b)
- Briumvi™ (ublituximab)
- Copaxone® (glatiramer acetate)
- Extavia® (interferon beta-1b)
- Glatopa® (glatiramer acetate)
- Kesimpta® (ofatumumab)
- Ocrevus Zunovo™ (ocrelizumab and hyaluronidase)
- Plegridy® (pegylated interferon beta-1a)
- Rebif® (interferon beta-1a)
Oral treatments
- Aubagio® (terlflunomide)
- Bafiertam™ (monomethyl fumarate)
- Gilenya® (finglolimod)
- Mavenclad® (cladribine)
- Mayzent® (siponimod)
- Ponvory™ (ponesimod)
- Tecfidera® (dimethyl fumarate)
- Vumerity® (diroximel fumarate)
- Zeposia® (ozanimod)
Intravenous (IV) treatments
- Briumvi® (ublituximab)
- Lemtrada® (alemtuzumab)
- Novantrone® (mitoxantrone)
- Ocreveus® (ocrelizumab)
- Tysabri® (natalizumab)