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Area Postrema Syndrome!

I know it's very uncommon but I am really desperate to find someone who can relate!
A little history about my case: before I was diagnosed-ish with MS I've had some episodes of nonstop vomiting that lasted for days up to a couple of months along the years and I was always told by specialists that it's psychological as they found no bilological cause. These episodes and due to the number of lesions on my cervical spine which was a lot more than the ones on my brain lead the all the well known neurologists in my country to be unable to decide if it's MS and NMO; Neuromyelitis Optica is a very rare autoimmune disease that also primarily affects the central nervous system and is sometimes misdiagnosed as MS. However, symptoms of NMO are usually more severe MS and they actually include Area Postrema syndrome as one of the main -The area postrema (AP) has been implicated as the trigger zone for vomiting-, so, the neurologists decided there's no way to specify my diagnosis and I was prescribed Rituximab which is a very intense treatment but supposedly works for both disease.
Later on, I was finally assured it's MS by a famous neurologist in London and it was explained to me that although I definitely have MS, the position of my lesions caused inflammation of the area postrema and there's no known treatment.
Any MS patient here got Area Postrema syndrome and is suffering from constant vomiting with every single meal or sometimes even without?
Share your experiences please if you have any or even know of someone who does.

  1. My heart goes our to you, . Constant vomiting with no end in site much be difficult to make peace with. I hope you find others in the community to connect with and that your doctors eventually find a way to treat it. Gentle hugs. - Lori (Team Member)

    1. , you are right; your condition is quite rare! I have scoured all my "go to" places online to try to dig up some information or personal stories for you and have found . . . nothing. 🙁 I am so sorry I can't be of more help. But, I am glad you posted here because our community is constantly growing and I have no doubt that someday, your post will help someone else.


      Have you and your physician found *anything* that brings you any relief?


      Best, Erin, MultipleSclerosis.net Team Member.

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