Bafiertam (monomethyl fumarate)
What are the ingredients in Bafiertam?
The active ingredient in Bafiertam is monomethyl fumarate.1,2
How does Bafiertam work?
Bafiertam is known as a fumarate therapy. The way Bafiertam works is not entirely understood. It is thought to affect the immune response, making it less inflammatory. Bafiertam also may protect against brain and spinal cord damage.1
What are the possible side effects of Bafiertam?
The most common side effects of Bafiertam are:2,3
- Rash and itching
- Stomach pain
Ask your doctor about taking aspirin to prevent flushing.
More severe side effects can occur. These may include:2,3
- Allergic reactions: If you experience hives, difficulty breathing, or swelling of the face, lips, or tongue, get emergency medical help right away.
- Progressive multifocal leukoencephalopathy (PML): A rare brain infection. This can lead to death or severe disability. Get medical help right away if you have weakness on 1 side of the body, clumsiness, vision changes, memory problems, confusion, or personality changes.
- Infections: This includes viruses such as herpes zoster (shingles) and central nervous system (CNS) infections.
- Low white blood cell count: Your doctor will order labs before you start taking Bafiertam, 6 months after you begin taking it, and every 6 to 12 months after that to monitor your white blood cell count.
- Liver problems: These can be serious and lead to liver injury. Your doctor will order blood tests before you start taking Bafiertam and during treatment. Tell your doctor right away if you have appetite loss, pain on the right side of your stomach, fatigue, dark-colored urine, or yellowing of the skin and eyes.
These are not all the possible side effects of Bafiertam. Talk to your doctor about what to expect or if you experience any changes that concern you during treatment with Bafiertam.
Things to know about Bafiertam
You can take Bafiertam with or without food.2,3
Swallow the capsule whole. Do not chew, crush, or open the capsules.2,3
Your doctor will monitor your treatment with blood tests.2,3
Before beginning treatment with Bafiertam, tell your doctor about all your health conditions and any other drugs, vitamins, or supplements you are taking. This includes over-the-counter drugs.
For more information, read the full prescribing information for Bafiertam.