, I am currently taking this medication and my next dose is waiting for me in the fridge for Monday. I still have to use my walker around the house and the wheelchair for long distances out the house, but am hopefully not getting any worse. Taking the shot is more convenient for me than going to the Ocrevus center. On the fourth evening after each shot, my stomach feels upset. And as of right now, I feel more tired a week before and a week after my shot. I have been on it for about six months now. The humidity and heat still bothers me, but hopefully Being affected by the heat and the cold will change for the better someday if at all possible. Take care and I hope everything goes well for you on Kesimpta. Oh yea, and for me, I call the pharmacy a couple weeks prior to my next dose to make sure I get it on time. They were a week late one month and three days late the following month.